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Associated syndromes: congenital heart disease, leukemia, premature Alzheimer's disease (same morphological changes).
Multiple fractures after birth, blue sclerae, thin skin, progressive deafness in some types (due to abnormal middle ear ossicles).
In some ancient African and Asian cultures, hermaphrodites were considered a bad omen or a curse and were killed at birth.
In other ancient cultures, hermaphrodites were regarded as semi-gods.
Aromatase deficiencies and maternal androgens are other causes of female pseudo-hermaphroditism.
A male pseudo-hermaphrodite has testicles and female ambiguous external characteristics.
Many plants and animals, particularly invertebrates, possess hermaphroditic characteristics and they have the ability to act as a male or a female.
The term “hermaphrodite” is applied to human beings who possess both male and female genitalia, however, this biological condition is very rare among humans.
There are three types of hermaphrodites: “true,” “female pseudo-hermaphrodite,” and “male pseudo-hermaphrodite.” The main difference among these three hermaphroditical types is the nature of the sexual organs.
Some hermaphrodites have a more dominant sex organ, while others have a combination of both sexual organs with no clearly-defined dominant organ.
The secondary sexual characteristics may also portray feminization and less virility.
The main causes of male pseudo-hermaphroditism include reduced tissue response to testosterone, maternal ingestion of estrogens, errors in the production of testosterone, and defects in androgen-dependent tissues.
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